Published on 30-10-2017

The skin is daily subjected to various stresses, such as pollution, cigarette smoke, UVA, UVB… which alter cells.

WE PROPOSE THE USE OF AUTOPHAGY AND/OR MITOPHAGY AS A NEW LINE OF SUBSTANTIATION

These cell recycling/detoxification pathways represent markers for monitoring the impact of these stresses on cells.

Indeed an aggression will stimulate these paths. A protective product may prevent the formation of damaged material within the cell and thus limit the activation of autophagy and mitophagy.

Specific markers are:
– LC3B, autophagy central protein,
– P62, main substrate,
– PINK1, mitophagy specific marker.

Additional markers such as MT1H, AhR, NRF2, HO-1, MDA… can also be studied in parallel to support your results.

BIO-EC Laboratory proposes to objectify the efficacy of your products through autophagy and / or mitophagy against environmental aggressions using:
– l’utilisation de la Pollubox® (Pollubox® newsletter),
– UVs irradiation.

To know more ask us our special Autophagy newsletter and do not hesitate to contact us for any information or request for a quote.