Tailor-made efficacy studies
Since 2006 BIO-EC Laboratory has been offering you in vivo studies on a panel of healthy volunteers representative of the population in terms of age and skin types. To meet more specific requests, we also have ethnic panels. All our studies are carried out in France.
Our laboratory is equipped with a large number of biometrology tools (corneometer, tewameter, AEVA-HE, etc.) enabling objectivation of cosmetic and dermatological claims.
Our cutaneous know-how today enables us to offer you detailed studies for reliable, impartial, high-quality results in compliance with Good Clinical Practice, for your objectivation requirements relating to:
For your tolerance tests our studies can be carried out under dermatological and ophthalmological supervision.
Our dermatologist, an expert in cosmetology, provides a critical view and uses cosmetic notions when appreciating the activity of your products.
Our cutaneous expertise enables us today to make our in vivo studies more thorough thanks to the histological and IT analysis of the samples taken during a study.
The specificity of our laboratory’s in vivo studies is founded on the development of surface sampling techniques providing complementary results to the biometrical results and enabling recourse to biopsies to be avoided.
In the case of interventional studies our laboratory can offer you comprehensive assistance when filing your dossier with the ANSM (French Agency for Medicines and Health Products Safety) and the CPP (Protection of Persons Committee).
Measurement of the hydration of the corneal layer.
Measurement of the skin’s mechanical properties (elasticity, firmness).
Measurement of the Trans-Epidermal Water Loss (TEWL).
Visual measurement of the distribution of hydration and analysis of the micro-relief of the epidermis.
Microscopic evaluation of desquamation.
Microscopic evaluation of the micro-relief with visualisation of the repairing of the cutaneous barrier and determination of a physiological age.
Visualisations:
Assays :
Analysis of the skin hydration rate and of the condition of the cutaneous barrier by spectroscopy.
Measurements, by 3D digitalisation of the body and face, of variations in volumes, forms, textures, wrinkles, etc. thanks to the fringe projection system.
Measurement of the cutaneous surface temperature
Elastomer replica enabling the width, depth and volume of the cutaneous relief to be measured thanks to the fringe projection system.
HD photographs enabling the texture of the skin, the quantity and intensity of the wrinkles, the brown specks, the quantity and dimensions of the pores, the porphyrins, red specks, etc. to be measured
HD photographs enabling the colour of rings around the eyes, resistance of make-up, coverage of a sun filter, etc. to be illustrated
Measurement of the density of collagen, melanin and haemoglobin.
Sensor enabling the anisotropy index to be measured.
Measurement of the intensity of colour, (a*, b*) and the lightness (L*).
Measurement of the colour, of special effect shades and the shine of the skin (L*a*b*C*h° and ΔE*).
Film enabling lipids of sebaceous origin to be collected and before and after-type type photographs to be obtained.
Measurement of the quantity of sebum by photometry (obtaining a score).
Measurement of the density of the dermis (%) and of the thickness of the epidermis (μm).
Measurement of the density, the thickness of hairs or hair, evaluation of the various hair growth phases (anagen, catagen, telogen).
Microscopic examination of the bulbs, the roots and the diameter of (body) hair and measurements of the melanin load.
Analysis of the structure of hair, of scales and of split ends.
Evaluation of the effect experienced, of the efficacy and of the cosmetic quality of the product via a web interface.
Evaluation of the effect experienced, of the efficacy and of the cosmetic quality of the product via a web interface.
Subjective self-assessment of the stinging sensation by the volunteer.
Measurement of the adhesion of particles by applying a powder (of known grain size) replicating pollution, followed by photographs taken before and after the products are applied.
Measurement enabling the cutaneous regeneration to be determined.
Lamp replicating actual conditions of exposure of the skin to blue light (420-470 nm). Measurement of the pigmentation caused by the exposure.
All our in vivo studies can be accompanied by a usage test, i.e. appreciation of the effect experienced, of the efficacy and of the cosmetic quality of the product by the volunteer. All our studies may also be carried out under dermatological and ophthalmological supervision.
Hydrating effect/regeneration of the cutaneous barrier functions/nourishing effect/reduction of uncomfortable sensations
Measurement of hydration using the MoistureMap®
Surface sampling
Observation of D’Squams (Diagnoskin system)
Carbonylated proteins from surface samples before application of a product
Carbonylated proteins from surface samples after application of a product
Anti-wrinkle/lifting/smoothing/restructured effect/redraws the oval of the face/toning/remodelling/visible reduction of the signs of ageing.
4D AEVA-HE® visualisation bench
Cutaneous micro-relief (Diagnoskin system)
Ultrasonography
Anti-rings/anti-bags/smoothing effect/reduction of lines, of rings and/or of bags/reduction of signs of fatigue/eyelid lifting/radiant look
Suitable for people who wear contact lenses.
VISIA-CR® eye contour photo
Anti-specks/lightening/shade brightness/self-tanning effect/evening/long-lasting/attenuation of red specks/soothing/anti-rosacea
Visualisation of melanin using D’Squam before treatment
Visualisation of melanin using D’Squam after treatment
Soothing/repairing/dermoprotective effect/reduction of discomfort sensation
Maturation of corneocytes from surface samples
Maturation of corneocytes from surface samples
Maturation of corneocytes from surface samples
Anti-pollution/detoxifying/protective/repairing effect/tone brightness/complexion/evening/anti-ageing/particle adhesion limit
Skin before application of coal particles
Skin after application of coal particles
Anti-blue light/protective effect
Measurement of the colour by spectrocolourimeter
Exposure to blue light
Cleaning effect/removal of make-up residues/cleanliness sensation
Suitable for people who wear contact lenses.
Efficacy of a make-up remover
Exfoliant/scrubbing/anti-imperfections effect/reduction of pore size/smoother skin/refined skin texture
D’Squam dry skin
D’Squam hydrated skin
Anti-imperfections/seboregulating/purifying effect/reduced shine/astringent effect
From surface samples: Blackheads
From surface samples: Porphyrins
From surface samples: Follicular keratose
From surface samples: Yeasts
Slimming/anti-cellulite/anti-sponginess/anti-orange peel/draining/smoothing/remodelling effect/inches loss/toning/sculpting/refining effect
AEVA-HE® body fringes projection
Anti-regrowth/refining effect/removal of all hair/smoothness sensation/reduction of the number of hairs
Medical hair removal equipment
Evened and corrected complexion/mattifying effect/healthy complexion effect
Clinical scoring of the face
Volumising/long-lasting/intense colour effect
Visia-CR® mascara photo
Non-stick/non-greasy/non-transfer/long-lasting/intense colour effect
Visia-CR® lipstick photo
Long-lasting/intense colour/quick drying effect
Visia-CR® gloss photo
Repigmenting effect/limiting of the appearance of white hair
Anti-loss/densifying effect
Detection using Trichoscan®
Anti-dandruff/deep cleaning/regenerating/fortifying effect/sensation of immediate and lasting freshness/scalp protection effect
Visualisation of dandruff
Purifying/deep cleaning/seboregulating effect/immediate and lasting freshness sensation
Sebum analysis
Volumising/shine effect/colouring resistance/smoothing/hydration/repair/restructuring/ supporting/fortifying/soothing/long-lasting effect
Visualisation of the scales
BIO-EC Laboratory has a location authorisation issued by the ARS (Regional Health Authority) permitting us to take charge of your studies on medical devices (class I, IIa and IIb), food supplements and tattooing products.
We undertake to offer you a tailor-made cost estimate, depending on the objectivation sought for your product.
We can assist in your regulatory processes with the ANSM and CPP (Protection of Persons Committee) by constituting and filing your regulatory dossier.
Clinical scoring of teeth
Medical devices
Food supplements
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